After two remarkable editions, BOOK 2.0 returns for its third edition, establishing itself as a space for reflection and innovation on the future of books and literacy. This year, hosted at the Champalimaud Foundation, an emblem of scientific and technological excellence, highlighting the intersection between knowledge and innovation. We will debate how artificial intelligence, the democratization of knowledge, sustainability, and the reinvention of literary spaces are transforming our relationship with books, inspiring innovative solutions and policies for the future of the sector and contributing to a more informed society that is better prepared to face today’s challenges.